# Radyalis Software Overview

All Radyalis software is architected for unparalleled performance on conventional workstation and/or server platforms without the added cost and complexity of hardware acceleration. The Radyalis _Plum_ Monte Carlo dose calculator has been designed from the ground up to be highly scalable across all computing platforms, from laptops and single workstations through high-performance computing clusters and cloud platforms.

Very high parallel performance with upwards of 80% parallel efficiency has been demonstrated on a 64-node AWS® cluster. _Plum_ easily integrates with third-party applications via a dynamically linked library, a peer-to-peer interface communicating over standard secure sockets, or as a standalone application utilizing industry-standard input and output formats. Radyalis’ dose calculation engine can be used for all treatment plan types including Cyberknife®, Intensity-Modulated Radiation Therapy (IMRT), and Volumetric Arc Therapy (VMAT).

## Volumetric Arc Therapy Example

A thoracic carcinoma case is shown with a single arc comprised of 75 distinct control points describing the VMAT arc around the patient. The Radyalis _Plum_ dose computation engine calculated the dose deposited to a 2% statistical uncertainty in the patient volume in 178 seconds running on a single 18-core i9® processor. The following video shows the dose accumulation as the computation proceeds along the arc:

[Video Player](/content/wp-content/uploads/2018/03/vmat.mov)

The following screenshot shows the CT of the case under examination at the PTV. The isodose lines at the area of peak dose deposit for both the _Plum_ calculated dose (dashed lines) as well as that computed by the TPS (solid lines) are in excellent agreement.

Finally, the DVH plots comparing the Radyalis-calculated dose with the TPS dose are virtually identical for both the PTV as well as organs-at-risk.